PRE2019 3 Group18

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Group Members

Name ID Major Email
Kasper de Bruijn
1333046
Applied Physics
k.j.d.bruijn@student.tue.nl
Nick Jansen
1260731
Computer Science and Engineering
n.j.jansen@student.tue.nl
Davide Fabbro
1255401
Electrical Engineering
d.h.fabbro@student.tue.nl
Kamil Musiał
1283073
Computer Science and Engineering
k.musial@student.tue.nl
Milan Koumans
1256041
Electrical Engineering
m.koumans@student.tue.nl

Planning

Meetings held on Mondays and Thursdays. Tasks specified in the table have to be completed before the given meeting.
KdB = Kasper, N = Nick, D = Davide, KM = Kamil, M = Milan

Week Monday (morning) Thursday (afternoon)
1 -- --
2 ALL: Form a group, decide on the subject
  • KdB: Making questionaire diabetics (to discuss/improve during the meeting), plan visit to diabetes centre
  • N: find and gather info about similar projects on the wiki, gather ideas about app functionality
  • KM: Create wiki template, research state-of-the-art diabetes technologies
  • D: Research diabetes and needs of diabetics (IO for App)
  • M: gather ideas about app functionality
3
  • KdB: Write down the users part of the wiki, prepare for the meeting with diabetes center
  • N: List on the wiki all gathered requirements, functionalities, ideas what the app does; Help with app development plan
  • KM: Create app development plan, start setting up the project and its repository
  • D: write down the milestones and deliverables section on the wiki
  • M: write down the problem statement on the wiki
4
5
6
7
8
9

Subject

Problem statement

WHO, short for World Health Organization, published an article on 30 October 2018 named ‘Diabetes’ (REF1). The article stated some key facts about diabetes. For example, the number of people with diabetes changed from 108 million to 422 million in 34 years. This is a rather concerning number, especially with the fact that diabetes can be treated (note: not cured!) and its effects can be delayed or even avoided with the help of a medication, a healthy lifestyle; a healthy diet with good physical activity and with the help of proper, professional screening of the patient. Present-day these challenges can be tackled properly, but the USE-aspect still has a lot of improvements to undergo. Later in this section we will look more in depth into the USE-aspect of problems with current technology.

Diabetes is a well-known disease, but there is still a lot of ignorance about the disease. Diabetes is a disease which occurs when the amount of glucose in your blood is too high. Having too much glucose in your blood for a long period of time can cause health problems. Diabetes is a general name for the diseases, it defines severel types of diabetes. Although there is no cure for diabetes (yet), a person can manage their diabetes to stay healthy and will be safe from its fatal consequences.

A lot of people undergo constraints because of the disease and with the help of technology products will make lives easier for diabetes patients. Diabetes patients first of all need to take medicine, depending on their type of diabetes (REF2). Also, they have to follow a personal diet matching with their diabetes type (REF2). This is a very important step for the treatment of diabetes and it requires a lot of effort from the patient. The diet has to be very specific, healthy and available to the patient. Problems with a good diet for a patient could be that a person is allergic to certain food, the diet does not provide a complete diet with all necessary vitamins or the food itself is too expensive for the person or even not available to the patient in his current location. These are all some technical issues that can arise when focusing on a good diet. But also the USE-aspect of technology to help patients is a big part. The app has to be user friendly and clear for people to use it concisely and correctly. Wrong data or mere laziness due to the app being hard to understand is disadvantageous and could potentially be fatal to patients. That is why this is an important problem which needs to be solved.

REF1 : [1]

REF2: [2]

Objectives

- Researching the state-of-the-art on diabetes

- Researching the needs of a diabetic patient

- Creating an app to assist these people with their diet

Users

- People who have diabetes and could use assistance with their diet

The application we aim to develop has a clear group of users; diabetic patients. Approximately 1,2 million Dutch people have diabetes. There are two types of diabetic patients, called type 1 and type 2. About 90% of all diabetic patients are type 2 diabetics. For now, our focus is on the patients of type 1 diabetes, which is the more severe form. These people need a specific diet and have to regulate their blood sugar level by administering insulin. These patients will probably benefit from a wellmade application that can support them with their diet and blood sugar regulation. We will try to find out how these people can be best supported by an application, and what their needs are going to be. An interview with the patient-communication advisor of Diabeter Eindhoven, and diabetic patient type 1 herself, Wietske Wits, has been held. She has elaborated on the user needs she finds important.


The interview

Diabetes has influence on everything; it has been estimated that being diabetic adds about 150 decisions every day. These decisions revolve mostly around stabilizing blood sugar levels, like when to add insulin, what to eat, wheter or not to work out. There are 42 factors that influence blood sugar levels, so many things have to be taken into account (think of hormonal cycle, emotions, stress and adrenaline). You can never take one day off, the difficulties are constant.

At the moment, the institute Diabeter only advises carb counting applications. There are many applications and a variety exists that is of good use, but there are improvements possible:

- Since the struggle of being a diabetic is 24/7, it would be welcome to have some humour or encouragement in the application. It could also be used to buck someone up a little, making them feel supported.

- Many applications exist, but not often are they all inclusive. Having it all in one app would be a good improvement.

- Having the possibility to set the application up to send personalized reminders for taking insulin.

- Sometimes diabetics forget to take their insulin. These days, Facebook is often used to call out for other diabetics that are in the neighbourhood that could lend insulin to those that forgot it at home. The application we are developing could have a feature that people can contact each other if agreed to, to request assistance from other diabetics near using location.


Some things are important to take into account. When determining the target audience, it is important to consider age. Wietske advises to take a target audience aged between 18 and 50 years old. She also told us that it is important to always include a disclaimer saying that the application does not give off any medical advises. It is also important to note that there is a difference between patients using an insuline pump and patients using an insulin syringe, since these work in a different manner.

Besides these advises, Wietske Wits told us that some more people in the past have asked questions to do research or develop an app, but she has never heard back or seen results. She would be very interested to see something actually developed. She asked us to stay in touch and ensured that for follow up questions we can always approach her. The interview seems to be valuable for our research.

Requirement of the users

Our user requirements mostly depend on the functionalities our patient would need or want as a functionality of the app. The app has to make sure that the patient will follow a good diet (and that the patient will take his medicine), so the patient will have a (sort of) grocery list with the number of vegetables and other stuff the patient has to get. To help the patient to stick to this diet it will give many different examples of good meals to cook, but also to give the patient enough freedom to change some ingredients of those meals, like take other vegetables or choose chicken instead of pork. It should also be possible to choose a good meal from those example meals with a certain budget, so people do not have a lot of money, so it is very important to consider this as well. The app should also need the data of the measurement of the amount of glucose in the blood, based on these data the app can change the diet or call a doctor. It is not possible to measure the blood 24/7, so either a computer must simulate a person based on some measurements or the patient must measure his blood three or more times a day (the app can help remind this). This is very important because wrong data or forgetfulness of taking those measurements could lead to fatal problems.

To gather first-hand information about the requirements of the user an interview was held. The interview was held with the contactperson for diabetes in healthcare. The person has diabetes himself and acts as a communicationpoint for other parties who have questions about diabetes in the current healthcare system. The experience of diabetic patient is that has influence on their whole life. Around 150 moments a day the patient has to make decisions concerning their health due to diabetes; think about the concern for their bloodsugar-level in their blood. This has to be stabile and can be achieved with an insuline-pump, their diet or physical exercises. This constant attention towards these problems is very demanding of the patient throughout their day. There are around 42 factors which have influence on the bloodsugar level. Some very common ones are hormone cycle, emotions, tensions or stress due to work or adrenaline. There is never 'a day off' from the disease, it is always a danger to the patient.

So there are a lot of problems when having diabetes. Fortunaly for people with diabetes, there are already a lot of technologies to help a person. Think about automatic insuline-pumps which are connected to a bloodsugar-meter.

A type 1-patient does not need to follow a certain diet, but they do need insuline. They need this in two forms, namely one 'long-working' insuline shot and 4 'short-burst' insuline shots with meals. More and more people are getting an automatic pump-sensor device to control the insuline intake of the patient.

Some very important notes of the interviewed person where that people tend to forget to take insuline during mealtimes. This can be an improvement for current technology. Also, a carbohydrates-counter would be a fine addition to the current technology. The app can help make decisions about food. This remark is in accordance with the initial idea of improvement for our current technology. A remark which the interviewed person repeatedly emphasized on is that the disease is demanding the attention of the patient 24/7. Large leaps can be taken here, for example encouragement to the patient would be a fine addition or just plain humor. Nowadays, app are very concise and to the point. A more humain app is better for the person. Calculation of insuline according to the food the person wants to eat is also a good addition.

State-of-the-art

Diabetes applications

The market of diabetes applications on smartphones has grown immensely over the past years. Users can choose between many options, no matter which operating system is running on their phone. Presented research has focused on Android users, since our prototype will also be developed for that platform. The list below consists of some of the most popular applications. They were downloaded and tested, so that we would obtain some first-hand experience. At the end there is a paragraph summing up the general findings.


Calorie Counter - MyNetDiary, Food Diary Tracker [3]
alternative text
Made not specifically for diabetic people, but for anyone who wants to have better control over their diet. Biggest advantage is the very big database of foods, with the possibility of updates from users. Includes a barcode scanner that allows to scan the food package for easy calorie and nutrients entry.
The proposed (by the creators) way to use the application is as follows:
  • Set a weight goal
  • Enter a target date ( vacation, wedding, or reunion )
  • Get a calculated Calorie Plan
  • Log daily meals and exercise
  • Follow daily Calorie Budget
  • Reach your goal
The application is extensive and sophisticated. However, it lacks support for functionalities specifically in need by people with diabetes, such as measuring/logging sugar levels. Some of those features are only unlocked if the user buys the full version of the application. A subscription costs $9 USD monthly. Thus rendering this option attractive for our target user only if they are willing to pay.
mySugr - Diabetes App & Blood Sugar Tracker
link to Google Play
This application's target users are indeed people who struggle with diabetes. It was reported to be amongst the most used by the participants of this link study. It provides a vast range of activities. However, to fully benefit from the functionalities it is required to invest in the full version of the application. Some of the features are blocked or limited in the free version, for example only 5 food scan per day are allowed. This application supports
  • Blood sugar tracking
  • Meal logging
  • Insulin dosage calculation
BG Monitor Diabetes
link to Google Play
Functionalities available in the pro version (costs $4.99):
Supports reminders to check your blood or give insulin
Automatically calculates insulin dosages and total carbohydrates from multiple food servings
Creates reports and can email them to healthcare provider within app
Stores data on external could service for easy recovery
Health2Sync - Diabetes Care
link to Google Play
Support logging and tracking of various inputs, such as blood sugar, blood pressure, weight, medication, diet, exercise, and mood.
Distinctive feature of the application is the possibility of inviting 'partners' that have oversight over the gathered statistics and can provide encouragements.
Diabetes Connect
link to Google Play
Simple interface, easy to use and intuitive to navigate. Tracking weight, blood sugar, meals, insulin injections, medication. Supports synchronization over multiple devices.
Can enter multiple data at once: blood glucose, insulin, and carbohydrates
Glucool Diabetes
link to Google Play
Highly customizable: custom insulin, medication types, and exercise types
Can enter multiple data at once: blood glucose, insulin, and carbohydrates
Premium version costs 7.99$, unlocks all features such as creating graphs


The market of applications for diabetes users is very well developed. Users have a choice between many options that enable them to track every aspect of their illness. The basic options for every app include logging of information such as blood sugar level, insulin, meals, medication and activities. Some of them provide the option to generate graphs about the data. Most of the applications are not free, if the user want to make us of all the features they have to pay. The price range varies from 3$ one time purchase to 10$ monthly subscription plans.

Usage of applications by people with diabetes

Nowadays smartphones are considered widely available and most people in highly developed countries make use of them. The total number of smartphones users worldwide was estimated to be 2.90 billion in 2018 [4]. The market for smartphone applications dedicated for people struggling with diabetes has also grown immensely. Only from 2011 to 2014 the amount of applications has risen from 80[5] to an astounding amount of over 1000 [6]. In 2018 this number was already around 5000(!), 3600 updated regurarly[7] However, according to the same research of the market, only 1.2% of the target group (people struggling with diabetes) were using an app in 2011. It was predicted that this number will increase to 7.8% in 2018. We could not find any recent research that would confirm this claim. This number of users also raises some suspicions from our side, since not all people have access to smartphones and not all people are skilled enough to use them. We suspect that taking these things into account the real percentage might be considerably higher.

Many reports indicate that the current state of the art for diabetes application is far from ideal. Practice standards are not met by these applications [8], causing a lower than expected number of users. The standards accepted by the market include:

  • Personalization, i.e. modifiability, how much control does the user have over how the data is displayed and what information is gathered and shown in the first place
  • Feedback, for example about the progress. The social aspect, connecting to other users is also very important.
  • Feature coverage. An ideal application should have all the needed features in one place, users will not use several apps
  • Integration. Supporting multiple platforms and devices, connecting to external devices such as glucose meters
  • Motivational system. Related to the social aspect, encouragement from the application and other users has proven to have a positive impact
  • Ease of data input. Effortless usage
  • Design and user experience, aesthetics

Those standards were tested in a study done by Chomutare et al. [9]. They also concluded that personalized education is an underrepresented feature in diabetes mobile applications. No studies evaluating social media concepts in diabetes self-management on mobile devices was found, and its potential remains largely unexplored. Again, this touches upon the issue of diabetes applications being 'passive', instead of providing targeted support for users.

The market is full of apps of dubious quality, but we still wanted to determine whether

  • people are using these apps in the first place
  • apps help improve their self-care

Research about these two matters is presented below.
For our project it is important to establish whether there is a relation between using diabetes apps and quality of health. A study[10] published in March 2019 was conducted to answer this question. From November 2017 to March 2018 an online survey was conducted. "One thousand fifty two respondents with type 1 and 630 respondents with type 2 diabetes mellitus (DM) entered the survey. More than half, 549 (52.2%), and one third, 210 (33.3%), of respondents with type 1 and 2 DM, respectively, reported using diabetes apps for self-management. To measure how participants took care of themselves a questionnaire from the Summary of Diabetes Self-care Activities was used. It included positions such as “general diet”, “specific diet”, “exercise”, “blood glucose testing" and “smoking”. Using diabetes apps for self-management was positively associated with higher self-care behaviour in both types of diabetes. Respondents tend to care more about their health if they are using an application. In other words, applications aid them in improving their lifestyle. Similar conclusions were made by Krishna and Boren [11] after investigating a comprehensive list of studies that evaluated the use of cell phone for health information. Using mobile phones results in improvement of health outcomes, because users become more knowledgeable and aware of their disease. It helps by providing care, support and aids in self-management improvements.

These findings support our motivation for the project - we want to help people with diabetes and improving smartphone applications can make a difference.
There may be many different apps to choose from, but most of them lack crucial functionalities[12]. From all the apps that were tested (371) all of them supported blood glucose level recording. However, alerts about hypoglycemia or hyperglycemia were found in 58.8% of apps, where only 20.7% and 15.4% supported an action prompt for hypoglycemia and for hyperglycemia respectively. Thus upon further investigation we see that only a very small percent of all apps has more advanced features implemented. Admittedly, the situation has improved. In 2011 the Android Market had no apps that offered direct data input from glucometers [13] and tracking insulin was an option only in 45% of the applications.

From our perspective the most crucial features are missing, those relating to autonomous actions of the application/system. Most of the apps can be used as sort of a logbook, allowing users to keep track of various things. There is however no active feedback from the applications, such as advices on what to do if the patients' blood sugar level drops below a certain level. There is evidence [14] confirming that active feedback and a care system that supports making clinical decisions achieves better results than just logbook based aids. This study performed a trial with adult patients that suffer from type 2 diabetes. Patients were assigned to one of two groups: mDiabetes or pLogbook (paper logbook). After 24 weeks there was a noticeable difference between the HbA1c levels in those two groups. The implementation of the mDiabetes for patients with inadequately controlled type 2 diabetes resulted in a significant reduction in HbA 1c levels. The mDiabetes group ex- hibited a lower blood glucose level at prebreakfast, prelunch, and postdinner than the pLogbook group did.

Approach

Milestones

Week 1

  • Form a group

Week 2

  • Choose a subject, make it concrete.
  • Update the wiki page with all the basic information (problem statement, objectives, users, deliverables, milestones)
  • Prepare a meeting with a person from the diabetes centre
  • Make a separate plan of the application development process

Week 3

Week 4

Week 5

Week 6

Week 7

Week 8

Finish writing our wiki and give the presentation of our project

Deliverables

The literatures

Logbook

Week 1

Missed because of problems with group forming

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Week 2

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 user research(2), preparing interview(2), meetings(2) 6
Nick Jansen 1260731 Working on wiki(1) 1
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 Meeting Monday(2), Meeting Thursday(2),
wiki template (1), research state-of-the-art diabetes technologies (5)
10
Milan Koumans 1256041 Meeting Monday(2), Meeting Thursday(2), defining problem statement and research about diabetes (4) 8

Week 3

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 Having an interview and working this out(3), researching used needs and possibilities for application(3), adding interview and user needs to wiki(1) 7
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 Research on diabetes apps usage(4) 4
Milan Koumans 1256041 ... 0

Week 4

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Week 5

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Week 6

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Week 7

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Week 8

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Week 9?

Name Student number Activities (hours) Total time spent
Kasper de Bruijn 1333046 ... 0
Nick Jansen 1260731 ... 0
Davide Fabbro 1255401 ... 0
Kamil Musiał 1283073 ... 0
Milan Koumans 1256041 ... 0

Minutes

Minutes

References